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Deaths from ovarian cancer decline in the world, but grow in Brazil

Deaths from ovarian cancer decline in the world, but grow in Brazil

In addition, there was also a decrease in the number of women undergoing hormone replacement therapy (HRT), used to ameliorate menopausal symptoms. In this sense, improving the diagnosis and treatment for ovarian cancer is essential for the number to continue to fall.

The researchers analyzed data on deaths from ovarian cancer from 1970 available from the World Health Organization. that in 27 countries in the European Union, mortality rates decreased by 10% between 2002 and 2012, based on more than 100,000 women.

In the United States, the fall was even greater: around 16%. In Canada, the ovarian cancer mortality rate decreased by 8%. In Japan, the least expressive rate was recorded at only 2%.

However, the pattern of decline has been inconsistent in some areas of the world, such as in Latin American and European countries. Among European countries, the percentage reduction ranged from 0.6% in Hungary to over 28% in Estonia, while Bulgaria was the only European country showing an apparent increase. In the United Kingdom, there was a 22% decrease in mortality rates.

Latin American countries tend to have lower rates of ovarian cancer deaths. Argentina, Chile, and Uruguay showed decreases between 2002 and 2012, but Brazil, Colombia, Cuba, Mexico and Venezuela had increases in mortality rates. A 2013 data from the National Cancer Institute (INCA) shows that in Brazil about 3,283 women die from ovarian cancer.

"It is likely that the decrease is due to more uniform use of oral contraceptives across the continent as well as reproductive factors, such as how many children a woman has. However, there are still notable differences between countries such as Britain, Sweden, and Denmark, where more women started taking oral contraceptives earlier in the 1960s. other countries in Western and Southern Europe, such as Spain, Italy and Greece, where the use of oral contraceptives started much later and was less widespread, "says Professor Carlo La Vecchia of the University of Medicine in Milan, Italy.

Researcher Dr. Eva Negri, Head of Epidemiological Methods at IRCCS - Istituto Ricerche Farmacologiche Mario Negri, in Milan, Italy, added: "Women in countries such as Germany, the United Kingdom and the United States were also more likely to use hormone replacement therapy to ameliorate menopausal symptoms than in other countries. The use of HRT declined after the Women's Health Initiative report in 2002 and highlighted the increased risk of cardiovascular disease as well as breast and ovarian cancer. This may also help to explain the drop in mortality rates among middle-aged and older women in these countries. "The study shows that in countries where contraceptives are most widely accepted or used long-term, middle-aged or older women are less likely to have this type of cancer.

Researchers predict that the ovarian cancer mortality rate will be standardized for a number of countries by 2020. They expect a decline 15% in the USA and a 10% decline in the EU and Japan.

Professor Paolo Boffetta at Mount Sinai University of Medicine in New York, USA, commented: "The conclusions of Professor La Vecchia and his colleagues are important because they show how the use of hormone treatments has an impact on ovarian cancer mortality for the population. As we understand ways to prevent the causes and progression of this cancer, and the faster we can develop new strategies for early diagnosis and provide new treatment options, the better our ability to reduce the ovarian cancer mortality rate. "


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