Type 3 Diabetes: When Too Much Sugar Affects the Brain
The term Type 3 diabetes is a proposed term that indicates the insulin resistance in the brain caused by Alzheimer's disease. Although a little complicated to understand, we must first know that this is not a universally accepted term for the medical community, but it carries with it a very important concept: that of joining the brain to Diabetes.
Let's start with Alzheimer's? Well, Alzheimer's disease is one of the causes of dementia, that is, loss of mental ability that interferes with quality of life. There are several diseases that cause dementia, and Alzheimer's is one of them.
The big X of the question, and what researchers always look for, is to understand the cause of Alzheimer's and its consequent loss of neurons. And the research has come to the point of understanding that abnormalities in neurons, and therefore their loss, could be related to a very special type of Diabetes, affecting only the brain.
Understanding the types of diabetes
When we talk in Diabetes, we most commonly know 2 types:
- Type 1 Diabetes : this is due to the lack of insulin in the body, since insulin-producing pancreas cells (called Beta cells) are destroyed by an autoimmune process , where the body itself selectively attacks these
- Type 2 Diabetes cells: it occurs most often in adults, it is first caused by insulin resistance. In these patients, the pancreas even produces insulin, and often in excess, but this insulin becomes weak due to the process of resistance. And resistance is triggered by weight gain, sedentary lifestyle, and the person's own genetics in most cases. Over time, and worsening insulin resistance, the pancreas may go into exhaustion and then insulin shortage will occur.
Type 3 diabetes would be a form of diabetes related to insulin resistance only in the brain, unlike type 2, where there is insulin resistance in the whole body. And this situation of insulin resistance only in the brain would be implicated in the degeneration of the neurons mainly because a lack of insulin could also occur in the cerebral environment.
With less insulin there is greater loss of the synapses, which are the communications between the neurons, and there is loss of the plasticity of the neurons themselves, with a lack of production of the neurotransmitter Acetylcholine, one of the main means of communication between them.
Increasingly, studies have pointed to the intimate relationship between glucose uncontrol and glucose related metabolism as causing or aggravating factors of some diseases.
Going by the classic complications of Diabetes such as neuropathies or retinal involvement, for example, to implications in other organs that have not been closely related to glucose control.
Maintain blood tests, make regular visits and seek treatment in the event of symptoms, be am or metabolic, hormonal or neurological is always a key step in the prevention and control of various diseases.
According to studies recently published in the United States, about 10% of the population of developed and developing countries has a deficiency of vitamin D. This deficiency increases by approximately four times the chances of falls, bone fractures, depressive symptoms, colon cancer, and cognitive (memory and reasoning) problems.
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