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Excess hair in women may be a sign of disease

Excess hair in women may be a sign of disease

Hirsutism is one dysfunction that affects about 10% of women and is manifested by the excessive growth of terminal hairs in typically male areas, such as supralabial, beard, pectoral, back, abdomen, buttocks and inner thighs.

Terminal hairs are thick , long and pigmented. They may be dependent on androgens as in the above-mentioned or independent areas, as in the case of eyelashes and eyebrows. There are still two other types: yarrows, extremely thin hairs covering the skin of the fetus; and velus, which are soft, small, thin, and poorly pigmented.

Hirsutism should be distinguished from hypertrichosis, which corresponds to excess velus hairs uniformly distributed throughout the body, which is not due to excess hormones masculine. The presence of hirsutism may be linked to increased production of androgens, such as testosterone, dihydrotestosterone, androstenedione, DHEA, and hypertension. DHEA-S. However, often these hormones are normal and it is not possible to determine the cause of the disorder, which is called idiopathic hirsutism. In this case, carriers are believed to have increased sensitivity of the hair follicles to the normal amounts of androgens.

Related Problems

Excess hair alone, although not a serious health problem, is aesthetically uncomfortable for most women, inducing emotional disorders and low self-esteem.

In addition, it can be a sign of several diseases, especially when there is also virilization, ie presence of acne, temporal baldness, thickening of the voice , growth of muscle mass and / or clitoris.

Some possible diseases related to hirsutism are polycystic ovary syndrome (the most common), congenital adrenal hyperplasia, Cushing's syndrome, obesity, increased prolactin, and even some In addition to the aforementioned reasons, the use of drugs such as danazol, diazoxide, minoxidil, male hormones, tamoxifen, streptomycin, and phenytoin may be another cause of this problem.

It is worth remembering that genetic factors and ethnic origin also influence the growth of male pattern hairs in women. For example, while Asian and light-skinned blondes generally have the scarcest, Arab or Mediterranean-born women tend to have more hairs irrespective of the increase in androgens. In general, in this case, when there is in fact hirsutism, it is modest.

Several elements are relevant in the clinical history for the investigation of hirsutism, such as ethnicity; presence of family history of the problem; age of onset and rate of progression of hair growth; regularity of menstrual cycles; insulin resistance; the presence of virilization and the use of drugs capable of stimulating sexual hair.

For example, the appearance of this disorder slowly and progressively from puberty, associated with menstrual changes, suggests polycystic ovary syndrome. On the other hand, the presence of mild hirsutism, which had a slow development in a woman with regular menstrual cycles, normal and fertile ovulation suggests idiopathic hirsutism.

Sudden and rapid development of hirsutism, accompanied by virilization, is suggestive of tumors adrenals or ovaries capable of producing large amounts of androgens.

The investigation of diseases should be performed in women with moderate or severe hirsutism or hirsutism of any degree associated with one of the following changes: menstrual irregularity and infertility; central obesity (abdominal circumference greater than 88 cm - see article Types of obesity: know and differentiate);

For the proper diagnosis and treatment of hirsutism, endocrinologist evaluation is very important.

Common causes of hirsutism

Polycystic ovarian syndrome

Idiopathic hirsutism

Uncommon Causes of Hirsutism

  • Drugs: Danazol, Androgens, Phenytoin, etc.
  • Congenital Adrenal Hyperplasia: 21-OH, 11-beta-OH and 3-beta-OH

Hyperthyosis

  • Tumors ovarian tumors
  • Leydig cell tumors
  • Hilar cell tumors
  • Arrenoblastoma
  • Adrenal tumors
  • Severe insulin resistance syndromes
  • Hyperprolactinemia
  • Cushing's syndrome

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