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Eye color may indicate increased risk of cancer

Eye color may indicate increased risk of cancer

A new study by scientists at the Ohio Central University of Medicine in the United States has identified the first evidence of a strong association between eye-related genes and the development of ocular melanoma.

About 2,500 people are diagnosed annually with this disease in the United States. Previous research has suggested that this type of melanoma is more common in white (caucasians) and light-eyed.

However, the genetic mechanisms of the development of this cancer were largely unknown. The data collected suggests that genetic factors associated with pigmentation of the eyes and even the skin may increase the risk of ocular melanoma in a person. "This is a very important finding that will guide future research into exploring gene interactions pigmentation with other genetic risk factors in tumors not related to sun exposure, such as ocular melanoma, "says Abdel-Rahman, PHD of the Ohio State Cancer Center in the United States. more than 270 patients with ocular melanoma. Although there is no clinical connection linking this type of tumor to skin cancer, in this study the researchers sought to find genetic factors shared by both diseases.

There were 29 inherited genetic mutations that are related to skin melanoma, so that it was determine if there is a risk associated with ocular melanoma. "The genetic predisposition to ocular melanoma was considered restricted to a small group of patients with a family history. Now, our data show the presence of new genetic risk factors associated with this disease in a general population of patients with ocular melanoma, "says Kirchhoff, PhD of the Perlmutter Cancer Center, NYU University of Medicine, in the United States. study may generate national and international funding to conduct a more comprehensive and organized analysis of genome data in large groups of ocular melanoma patients. "

" This type of collaboration is extremely important in understanding the genetic risk factors of ocular melanoma This has important consequences not only for the prevention or early diagnosis of the disease, but t also for therapies for patients with the disease, "says Kirchhoff.


Anal itching can range from skin irritation to more serious diseases

Anal itching can range from skin irritation to more serious diseases

Itching in the anal region, whose medical terminology calls anal pruritus, is a very frequent complaint, being described from the oldest medical manuscripts. The rich innervation in the anal and perianal region is believed to be the reason for sensitivity to potential local irritants. In general, pruritus tends to be more at night and is more frequent in men.

(Health)

Restorations Offer a Second Chance to Win a Smile

Restorations Offer a Second Chance to Win a Smile

It is a fact that genetics has a major impact on a person's health. But did you know that genetics can also determine how teeth develop? Characterized by very small teeth, microdontia is an oral health problem that often occurs in families. Adults affected by microdontia may have small teeth with spaces between them, making them look like deciduous teeth (milk teeth).

(Health)