FDA approves medicine that can treat different types of cancer
Last week, the Food and Drug Administration ), has granted approval for a cancer drug that takes into account the molecular feature of the tumor rather than where the cancer is located.
The name of the substance is Pembrolizumab, and is indicated for the treatment of adult and pediatric patients with tumors that have not responded to conventional treatment and exhibit microsatellite instability. In other words, tumors that contain within them an abnormality that affects the correct repair of the DNA inside the cell.
According to the FDA, approximately 5% of patients are identified with this type of biomarker. This indication is intended for patients with solid tumors who have progressed after treatment and who do not have satisfactory alternative therapeutic options. Treatment with Pembrolizumab could be more effective for this type of tumor.
According to Acting Director of the Department of Hematology and Oncology of the FDA, Richard Pazdur, this step is important for the cancer community. This is because the approval of treatments always took into consideration the region of the body where the tumor began, for example, lung or breast cancer. And now, a tumor biomarker-based drug has been approved regardless of the original location of the cancer.
Pembrolizumab has been approved for this new indication using the Accelerated Approval route under which the FDA can approve drugs for serious conditions in which the conventional medicines did not present a satisfactory result. Further studies are needed to describe the clinical benefits of a larger number of patients.
Everyone remembers with a smile on Grandma's face saying "watch out for the cold, boy! If this flu catches you ...". For the grandmothers and great-grandparents who witnessed the Spanish flu in 1918, a pandemic caused by the H1N1 influenza virus in which about 3% of the world's population died, it was no exaggeration to worry so much about the flu.
Results showed that more than two hours per day in front of the television increases the chances of developing type 2 diabetes and heart disease and, more than three hours, premature death. Every two hours more television per day, the risk of all these diseases rises to 20%, 15% and 13% respectively.
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