Male fertility also has a relationship with age
The advancement of age also influences male fertility. From the age of 40 the levels of testosterone begin to decrease by about 1% per year. The daily production of spermatozoa remains relatively constant, but sperm motility drops by 7% per year, also affecting the volume of ejaculation, which also decreases with age.
Another important point in this process is the fragmentation of sperm DNA that increases with age, which hampers spontaneous pregnancy and may also impact the procedure for assisted reproduction. The effects of these changes on male fertility are difficult to assess, since erectile dysfunction, decreasing frequency of sexual intercourse, and age may also affect the fertility of the couple.
For an idea, semen banks, for example , do not accept donors older than 50 years in Brazil. It is known that as men age, their fertility decreases to a lesser extent than is the case with women.
Quality control during sperm production is severe as men age, as changes tend to occur more often. The chromosomal abnormalities of the sperm increase especially between the sex chromosomes X and Y, which can be transmitted to the children. Single genetic mutations occur in sperm DNA and this causes rare diseases.
Even after successful conception, paternal age has been linked to other pregnancy problems. Abortion rates are twice as common among partners 50 years of age or older. Preterm deliveries (less than 32 weeks) and fetal deaths are twice as large in age compared to younger parents. In addition to single genetic disorders in offspring, a number of other complex disorders and congenital defects have also been associated with paternal age with an estimated overall risk of 20% over the lifetime of the offspring. aging of men. It is important to note that there is strong evidence that being an older parent leads to an increase in several adult diseases in children. These cognitive disorders include schizophrenia (5 times higher), autism (4 times higher), bipolar disorder (2 times higher) and attention deficit disorders (2 times higher).
For every patient seeking human reproduction it is important integrate the clinical settings of men and women. Therefore, it is very important not to waste time and do a joint evaluation, as this unit is extremely important for the effectiveness of the result.
During the study, medical records of an additional 77,000 women and 50,000 men, who had used analgesics, were analyzed. The researchers found that people who were constantly using analgesics called nosteroids, also known as NSAIDs, had a 51 percent greater chance of developing kidney cancer for more than 16 years.
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