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Get all your questions about hormone replacement

Get all your questions about hormone replacement

In a certain period of the life of women and men, very uncomfortable symptoms arise. This period, called menopause (for woman) and andropause (for man), represents the drop in sex hormone rates. At menopause, menstrual and ovulatory cycles end in women between the ages of 45 and 55, while in andropause, there is decreased production of testosterone in men after age 50.

With hormone replacement, symptoms are minimized such as malaise, cognitive loss (some women complain of memory loss, worsening depression and anxiety) and loss of bone mass (bone is getting weaker? osteoporosis). In the case of men, hormone replacement results in improved disposition and increased libido.

It is also worth mentioning that, as with all medical treatment, there are side effects.

Hormonal replacement should always be done with the follow up and orientation of the gynecologist for women and endocrinologist or urologist for men. In women, the treatment consists of the replacement of estrogen, which may be transdermal (gel or adhesive) or oral, combined or not with progesterone? only for non-hysterectomized women, that is, they have uterus. In the past, some studies have been done, including the Women's Health Initiative (WHI), which has shown some risks of hormone replacement as an increase in thromboembolic events (stroke risk and stroke), in addition to breast cancer. However, these studies used women outside the age range we normally currently indicate for hormone replacement (there were patients over 10 years after menopause), with very high doses of one type of oral estrogen that we no longer use. With regard to men, there is no evidence that testosterone replacement induces prostate cancer. What we do know is that men with neoplasia (early stage cancer) have total contraindication to replacement. Both breast and prostate cancers have "receptors" for hormones (that is, hormones can stimulate cell growth). But the scientific evidence shows that they are not able to generate (stimulate) cancer in normal cells.

To identify the need for hormone replacement, the endocrinologist makes a thorough examination-based evaluation. It is also worth mentioning that, as with all medical treatment, there are side effects, among them, increase of the endometrium (minimized effect with progesterone use), increase of triglycerides (oral estrogen only), fluid retention, blood pressure in women and prostate enlargement in men. Therefore, hormone replacement must always be indicated and supervised by a specialist in the area.


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