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Know HER-2 positive breast cancer

Know HER-2 positive breast cancer

The acronym HER-2 stands for factor receptor 2 of human epidermal growth. HER-2 is a gene that can be found in all cells of the human body, and this gene has the function of helping the cell in the processes of cell division. The HER-2 gene causes the cell to produce a protein called HER-2 protein, which sits on the surface of cells. From time to time, the HER-2 protein sends signals to the cell nucleus, telling it that the time has come for cell division.
In the breast, each cell has two copies of the HER-2 gene, which contribute to the normal functioning of these cells. However, in some patients with breast cancer, the appearance of a large number of HER-2 genes occurs within the breast cells. With the increase in the number of HER-2 genes in the nucleus, the number of HER-2 receptors on the cell surface will also be increased. This condition is known as overexpression of HER-2. Researchers have found that overexpression of HER2 contributes to the uncontrolled growth of cells, which is the hallmark of cancer. Patients who have this condition are called HER2-positive. HER2-positive breast cancer grows and spreads more rapidly. It is estimated that about one in five patients with metastatic breast cancer is HER2-positive (ie 25% of patients) and research recent findings suggest that HER2-positive patients are likely to have a more aggressive form of breast cancer.
This is why the determination of the patient's situation in terms of HER2 as early as possible is an important factor for the
How do I know if my breast cancer is HER-2 positive?
To find out if breast cancer is HER-2 positive, the doctor asks for an examination of the best options for treatment of metastatic breast cancer. at the time of the biopsy called HER-2 test. The HER-2 test will be performed in a pathology laboratory by a pathologist. Is there any special treatment for HER-2 positive patients?
Patients with advanced HER-2 positive breast cancer may receive special therapy with monoclonal antibodies, at the discretion of the oncologist. Monoclonal antibody therapy for this type of breast cancer has been shown to increase the survival of these patients. Roberto Hegg is a gynecologist and mastologist. Her vast experience relies on several clinical studies on breast cancer


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