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Metabolic syndrome increases risk of developing kidney disease

Metabolic syndrome increases risk of developing kidney disease

It was noticed that those with metabolic syndrome are 55% more likely to develop kidney problems, especially low renal function, an indication of disease in this organ. In addition, the risk of developing these problems grows according to the items of the metabolic syndrome, ie the more components that characterize the syndrome an individual has, the greater the risk of developing kidney disease.

The researchers concluded that metabolic syndrome may be an additional item in the analysis of doctors to detect kidney problems. For them, when an individual controls the syndrome - with healthy diet, exercise, excess weight loss, and lowering cholesterol, blood pressure and blood sugar - he can prevent kidney disease.

Previous clinical studies have examined the effects of some of these measures (such as lowering blood pressure and blood sugar) on kidney function, while others (such as exercise effects and weight loss) still need to be studied.

A patient is diagnosed with metabolic syndrome when it exhibits three or more of the following characteristics: high blood pressure, high blood sugar, excess body fat in the waist and abdomen, and good low (HDL) cholesterol. The syndrome comprises this group of abnormalities that increases the risk of people having diabetes, heart disease, stroke, and premature death, when these diseases occur together.

Risks of the metabolic syndrome

Since the 1980s, that frequent diseases such as hypertension, changes in glucose and cholesterol were associated with obesity. In addition, all these conditions had one thing in common: insulin resistance. Insulin is critical not only for controlling blood glucose levels, but it acts on the liver, fatty tissue, kidneys and blood vessels.

In insulin resistance, the individual produces the pancreatic hormone insulin, but this amount - even adequate - it does not act completely, and consequently disrupts the transport of glucose from the blood into the cells so that it can be used as a source of energy. In the person with insulin resistance, the body secretes larger amounts of insulin, seeking to "correct" this unbalanced action, but sometimes this mechanism is not efficient and may present as a pre-diabetes state, and even diabetes, taken by the increased concentration of both insulin and blood glucose.

All causes of the development of this syndrome have not yet been clarified, but some factors can be facilitators such as the unbalanced diet coupled with a sedentary lifestyle. Already it is known that an irregular diet and lack of physical activity propitiate the increase of cholesterol, with risk of depositing in blood vessels causing atherosclerosis. And, in the growing obstruction of the vessels there may be an increase or worsening of hypertension. On the other hand, studies show that obesity leads to an increase in triglycerides, progression to diabetes and potentially increased atherosclerosis, keeping the components of this syndrome always in a cycle that maintains the disease.What can it cause?

The importance of Metabolic Syndrome was due to the finding of its relation with cardiovascular disease. When present, the Metabolic Syndrome is associated with a general mortality two times greater than in the normal population and increases in three times the mortality from cardiovascular causes.


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