Microcephaly: 1st trimester of pregnancy may be time of greater risk
Many women wonder: what is the pregnancy period most risky for the Zika virus infection? The case-control study carried out in Paraíba shows, initially, that mothers who had Zika virus in the first trimester of pregnancy were more likely to have children with microcephaly. The Ministry of Health, in partnership with the government of Paraíba and the Center for Control and Prevention of Communicable Diseases (CDC) of the United States, continues with the analysis of blood samples collected in mothers and babies from Paraíba. Only after this stage will the final results be released. The initial result of the study, presented in João Pessoa (PB), also found no association of microcephaly with the exposure of products such as insecticides, for example.
"This study includes the investigation of people who were not affected by microcephaly "It is only after the processing of the collected blood samples, comparing the cases and the controls, that we can estimate with more clarity the risk of being affected by the disease and the relationship of Zika with microcephaly", explains the advisor of the Secretariat of Surveillance in Health of the Ministry of Health, Eduardo Hage.
The research, which began on February 22, counted on the performance of eight teams - composed of the institutions involved? who investigated the proportion of newborns with Zeca-associated microcephaly in addition to the risk of virus infection in 56 municipalities in the state. In all, 165 cases of mothers who had babies with microcephaly and 446 control cases (ie mothers and babies from the same region without microcephaly) were interviewed. Among infants, 52% are female and 48% are male, in the age range of 0 to 7 months.
Another study conducted by a research group on the Zika epidemic (MERG ) reported that, of 100 mothers of children with microcephaly interviewed in the State of Pernambuco, 59 reported exanthema (rash and redness) during pregnancy, a common symptom in people infected with Zika virus. The study was published in a scientific journal of the United States' Center for Communicable Disease Control and Prevention (CDC).
Undoubtedly, the most common cause of anemia in this setting is known as anemia of chronic disease. In it, pro-inflammatory substances are produced by the tumor and prevent the normal functioning of the bone marrow, a major producer of red blood cells. Treatment is directed at the tumor, however, sometimes the use of marrow stimulators (erythropoietin) helps manage it.
Shortness of breath or "dyspnoea" (medical term) is the sensation of that your breathing is not being satisfactory. In other words, the brain understands that the action of breathing (the act of breathing in and out of the air) is not enough to supply the body's demand. Dyspnea is not physiological and should be viewed with concern.
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