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New test drug may inhibit Alzheimer's protein

New test drug may inhibit Alzheimer's protein

In a survey conducted by the research laboratory A new drug was discovered that could inhibit senile plaques in the brain that would lead to Alzheimer's. The results were published in the journal " Science Translational Medicine ."

The large accumulation of beta-amyloid protein is known to be one of the factors that lead to disease, creating plaques in the brain. The new drug, called verubecestat, works to reduce these plaques, acting directly on the enzyme BACE1, responsible for the appearance of beta-amyloid. Preliminary tests, performed with 32 patients, showed a reduction of up to 80% in levels of this protein. This is not the first time they have tried to create a drug with this function, but so far, all drugs created have had serious adverse effects on patients.

For the first time an oral BACE1 inhibitor drug has been authorized for a new phase involving many patients: about 3,500. Phase 3 of the research should be completed by July 2017 and, if the results remain satisfactory, the pill may be marketed within three years.


Inadequate chewing may contribute to weight gain

Inadequate chewing may contribute to weight gain

Chewing is the first phase of the digestive process - its function is mechanical digestion, ie, food fragmentation, allowing the mixing of the food bolus with the saliva . This, in turn, will perform its function of lubrication and chemical digestion, facilitating swallowing. Remembering that in this process, good teeth and efficient jaw joints are important.

(Health)

New blood test may help detect breast cancer

New blood test may help detect breast cancer

Another study published by the Clinical Breast Cancer has proven the usefulness of Videssa Breast as a diagnostic complement to images of women with abnormal findings and has shown that it could potentially reduce biopsy use by as much as 67%. "The use of biomarkers for cancer detection is a major advance in the management of women with dense breasts and in navigating many diagnostic challenges.

(Health)