New Immunotherapy Treatment Shows Good Results Against Breast Cancer
The treatment would help the immune system recognize HER2 protein in breast cancer cells. Their approach involves the creation of the immune cell vaccine, called dendritic cells that are harvested from each individual patient and then used to create a personalized vaccine for each patient. P>
The researchers conducted clinical trials in 54 women with cancer of early HER2-expressing breast cancer to determine the efficacy of the treatment. To prepare the vaccine, the dendritic immune cells were separated from the blood of each of the women and injected into the patients once a week for six weeks in a lymph node, tumor or both.
The results showed that treatment was able to stimulate an immune response in most patients. Approximately 80% of the patients evaluated had a positive immune response and the vaccine was considered to be well tolerated and with low toxicity. However, there were adverse events such as fatigue, injection site reactions and chills.
In 13 patients immunotherapy through the vaccine had a complete response, ie the cancer was no longer identified in samples taken by surgical procedures. In addition, the greatest efficacy was in women with ductal carcinoma, one of the most common types of cancer.
The aim of the study is to help patients with early breast cancer by restimulating the immune system to recognize and target the HER2 protein yet during the development of cancer.
Furthermore, it is not yet known whether immunotherapy would be used to cure cancer definitively or just treat it. The drugs are recent, the patients they use have yet to be seen, so that they can eventually find out if the tumors return or not.
Journal of Virology , may lead to premature testing for bacteria, which, if found, can be treated and monitored against cancer before they became malignant, the researchers said. Continue reading on Colgate's website.
The Unified Health System - SUS now offers the women of São Paulo (SP) the test capable of detecting thrombophilia, which is the tendency that one has to suffer a thrombosis. This condition generates the formation of blood clots in one or more veins located in the lower part of the body, usually in the legs.