New Immunotherapy Treatment Shows Good Results Against Breast Cancer
The treatment would help the immune system recognize HER2 protein in breast cancer cells. Their approach involves the creation of the immune cell vaccine, called dendritic cells that are harvested from each individual patient and then used to create a personalized vaccine for each patient. P>
The researchers conducted clinical trials in 54 women with cancer of early HER2-expressing breast cancer to determine the efficacy of the treatment. To prepare the vaccine, the dendritic immune cells were separated from the blood of each of the women and injected into the patients once a week for six weeks in a lymph node, tumor or both.
The results showed that treatment was able to stimulate an immune response in most patients. Approximately 80% of the patients evaluated had a positive immune response and the vaccine was considered to be well tolerated and with low toxicity. However, there were adverse events such as fatigue, injection site reactions and chills.
In 13 patients immunotherapy through the vaccine had a complete response, ie the cancer was no longer identified in samples taken by surgical procedures. In addition, the greatest efficacy was in women with ductal carcinoma, one of the most common types of cancer.
The aim of the study is to help patients with early breast cancer by restimulating the immune system to recognize and target the HER2 protein yet during the development of cancer.
Furthermore, it is not yet known whether immunotherapy would be used to cure cancer definitively or just treat it. The drugs are recent, the patients they use have yet to be seen, so that they can eventually find out if the tumors return or not.
The bacterial life that populates the mouth of your neighbor is probably as different from yours as that of a person on the other side of the planet, according to an article in the journal Genome Research Researchers at the Max Planck Institute for Evolutionary Anthropology, Shanghai Biological Sciences Institutes (China) and China University of Pharmaceutical Sciences analyzed saliva samples from 120 healthy individuals from 12 different locations around the world.
The Journal of the American Medical Association has revealed that sleep apnea can cause mild cognitive impairment and even dementia in women. The analysis was led by scientists from the University of California, California, in the United States. The research was supported by 298 women considered to be mentally and physically fit and with an average age of 82 years.