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Obesity and sedentarism have a relationship with prostate cancer

Obesity and sedentarism have a relationship with prostate cancer

Prostate cancer is the second most common neoplasm in men and the third that kills the most. Alongside erectile dysfunction, stroke and stroke, it is one of the ghosts that haunts male aging. Nothing more sensible, therefore, than trying to take every possible measure to avoid the problem. When the goal is to prevent a disease, the first step is to identify the so-called risk factors. That is, knowing what conditions that, when present, increase the chance of the disease appearing. Parallel with cardiovascular disease, we can exemplify that high blood pressure is a risk factor for the development of stroke, stroke. Therefore, by controlling blood pressure levels, treating the hypertension, the risk of stroke decreases.

In the case of prostate cancer, the recognized risk factors are: age, black ethnicity, and positive family history. Those who are older, black, or have a brother, father or grandfather who had prostate cancer have a higher chance of developing this type of cancer compared to those who do not. Unfortunately, these factors can not be modified and indicate an earlier age to initiate so-called periodic exams: 40 years. The others can start at age 45.

On the other hand, there are situations that influence the risk of cancer and are susceptible of modification. Studies published in the scientific literature indicate that obesity, a high fat diet and sedentarism could favor the development of tumors in the prostate, including stimulating some types of tumors with a more aggressive behavior.

On the other hand, there are situations that influence the risk and can be modified. Studies published in the scientific literature indicate that obesity, high fat diet and sedentary lifestyle could favor the development of prostate tumors, including stimulating some types of tumors with a more aggressive behavior.

Obesity is related to cancer of the prostate. prostate cancer in different ways: it can mean a risk factor, it can interfere with the dosage of the prostate specific antigen (PSA) by causing a dilution of this substance in the blood, it can make difficult the examination of the rectal touch and the accomplishment of the biopsy of the prostate and, finally, may interfere with the tumor's behavior, interfering with the prognosis. The current challenge is to find, in addition to the risk factors, the prognostic indicators that allow the doctor to know early on which tumors to look for. deserve to be diagnosed and treated definitively

But what is the explanation for the interference of obesity on the prostate? The possible mechanism behind the negative influence of obesity on prostate tumors would be the hormonal alteration due to excess adipose tissue, which would cause changes in the levels of testosterone, estrogens, insulin, adiponectin, leptin and inflammatory substances, which together would cause a greater multiplication activity of the neoplastic cells. Recent studies have consistently shown that men with a body mass index (BMI) above 30 kg / m² have larger and more aggressive tumors compared to those with a BMI below 25. This observation, however, does not allow the definitive way that obesity causes more aggressive prostate cancer. There are other possible explanations: perhaps the fact that PSA is falsely reduced has delayed biopsy indication and consequently diagnosis and surgery to treat cancer, leading to the outcome of the study without meaningful cause and effect.The relationship between regular physical activity and the incidence of prostate cancer has a lower level of evidence in the literature. This means that not all study results point to the same side. Some have found no relationship between practicing exercise and having a lower risk of developing prostate cancer. Others suggested this protective effect of exercise, but the benefit disappeared when considering the influence of BMI on the findings. Finally, small articles suggest a lesser aggressiveness of tumors and a better prognosis among those who spend more time on aerobic physical activity compared to sedentary.

Is diet important in the prevention of prostate cancer? Several elements of the diet have already been associated with prostate cancer. No definitive way. Robust studies that identify the protective effect of a substance on its own are very difficult to perform, entail a long period of observation and are expensive. Therefore, caution should be exercised in the incorporation of this preliminary information.

Tomato consumption, more precisely lycopene, would have a protective effect on the prostate tissue. There are several articles that saw a benefit of lycopene. But there are some who failed to show a difference in relation to the group that did not ingest the substance. With the pooled analysis of the most relevant studies, there appears to be a trend favoring the consumption of lycopene to reduce the risk of prostate cancer.

On the other hand, higher calcium intake seems to be associated with an increased risk for aggressive tumors. A possible interference with vitamin D and parathyroid hormone could be the justification for this finding. The consumption of antioxidants was also evaluated in recently published studies. Vitamin E and selenium have not been shown to be effective in preventing prostate cancer. On the contrary, the group of men who consumed 400 units of vitamin E daily for about six years showed a tendency to increase in cases of prostate cancer.

The amount of saturated fat in the diet seems to correlate with the chance of developing prostate cancer. Even the omega 3 has been put as a villain in some publications, increasing the risk rather than reducing. This data is not always demonstrated in nutritional studies and there seems to be interference of other factors such as BMI and physical activity in the association of diet with prostatic diseases. Take care of your health and you will already be helping your prostate! It is worth remembering that obesity, sedentarism and dietary factors are closely related, and studying them in isolation is not a simple task. Of course, this is one of the reasons for conflicting results in the literature.

Therefore, know that despite the great advances of medicine in this area, these are still controversial subjects and the great efforts of the researchers. There are more doubts than certainties. The current challenge is to find, in addition to the risk factors, the prognostic indicators that allow the doctor to know early on which tumors deserve to be diagnosed and treated definitively. The theme may seem complex, but we can simplify it: do your part! Adopt healthy living habits! Feed yourself in a balanced way, exercise regularly, control your weight and you will certainly be improving your health, especially cardiovascular. As a matter of fact, you may still be preserving the health of your prostate. You only have to win!


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