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Caffeine stimulates enzyme that can prevent dementia, study says. Analysis found 24 compounds that can help reduce the impact of harmful proteins on the brain

Caffeine stimulates enzyme that can prevent dementia, study says. Analysis found 24 compounds that can help reduce the impact of harmful proteins on the brain

The results showed that mice that consumed coffee were able to produce the same enzyme levels as normal mice. In addition, caffeine has also improved the memory of genetically engineered mice to produce high levels of Tau. Thus, scientists believe that eliminating Tau protein is essential for combating neurodegenerative diseases. The researchers also discovered another compound that boosted enzyme production in the brain: rolipram. This is a drug whose development as an antidepressant was discontinued in the mid-1990s.

Other compounds found in the tests were ziprasidone, cantharidine, wortmannin, and retinoic acid. The effect of retinoic acid, derived from vitamin A, also performed well. According to the researchers, the finding may help in the creation of remedies that increase the levels of this enzyme in the brain, blocking the debilitating effects of neurodegenerative diseases. "Raising our knowledge about the pathways in the brain that seem to naturally cause the decline of this protein requirement is as important as the identification of compounds that could play a role in future treatment from debilitating mental disorders, "says Hui-Chen Lu, a professor of biochemical sciences who led the research.


Surgery is very delicate due to the high degree of infection in the brain tissues of the model

Surgery is very delicate due to the high degree of infection in the brain tissues of the model

Understand the case of Renata Banhara The problem of the model began due to an encephalitis, infection in the brain. In a press release, Ronéia Forte said that Renata "had a tooth that did not manifest itself. She was housed. As the tooth is porous, the bacteria entered and remained in the bone of the face and went to the brain and gave a sinusitis, also caused by a bacterium.

(Health)

Facts about diabetes and dry mouth (xerostomia)

Facts about diabetes and dry mouth (xerostomia)

Why does diabetes and dry mouth often occur in the same patients? Two of the main causes of dry mouth for people with diabetes are the side effects of medications and high blood sugar levels. Other causes, not directly related to diabetes, but which can aggravate the problem are: poor hydration, mouth breathing and smoking.

(Health)